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Kamalian Path-NP
Lab.
Section reveal fragments of
tissue including gray and white matters of cerebral hemisphere with a neoplasm,
the latter is composed of proliferated astrocytic glial cells. It is highly
cellular and pleomorphic, containing spindly and giant mononuclear and
multinucleated forms, at times having glassy and occasionally vacuolated
xanthematous, cytoplasm, juxtaposed with less cellular and less atypical
astrocytes at the periphery. The vessels are prominent and congested. The
neoplasm contains focal lymphocytic infiltration. Special stain reveals
abundant reticulin fibers between neoplastic cells.
Gross: The specimen consists of
numerous tissues the overall measuring 4 x 3.5 x 3 cm. R.S.S
DX: Pleomorphic
xanthoastrocytoma(grade I in new WHO classification).
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